OCP has created a huge and powerful computer-brain cyborg, the MIND (Massively Intelligent Neural Device) mixing human brain tissues and computer chips. In parallel, OCP is secretly supporting human gangs which are dealing a new synthetic drug, the BrainDrain. OCP's objective is to raise criminality in Detroit in order to defeat Mayor Thomas Croford, presenting themselves as the only entity that can restore peace... and finally take full control of the city.